Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

510 questions · 513 findings · 62 reviews · Headline outcomes only

No studies found 96 · 18.7%GRADE not reported 13 · 2.5%Very low 181 · 35.3%Low 121 · 23.6%Moderate 69 · 13.5%High 33 · 6.4%

ProSeal vs Classic laryngeal mask airway (LMA)

Inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

It is very uncertain whether proSeal changes inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) compared with classic laryngeal mask airway (LMA) (very low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Sore throat · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in sore throat compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Regurgitation · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in regurgitation compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review

Screening vs routine practice

Number of new diagnoses · vulnerable population: senior 65 years of age or older

Screening probably leads to higher number of new diagnoses: systematic screening vs routine practice compared with routine practice (moderate certainty).

2 findings from 1 review

Nitroglycerin vs no treatment

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Cardiac ischaemia indicated by ECG · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes cardiac ischaemia indicated by ECG compared with no treatment (very low certainty).

1 finding from 1 review