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Avatar Therapy showed no clear difference in global state: relapse (rehospitalised) – short term compared with treatment (low certainty).
Avatar Therapy showed no clear difference in leaving study early: for any reason compared with treatment (low certainty).
Avatar Therapy showed no clear difference in adverse events – anxiety – after first session – short term compared with treatment (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes clinical recurrence (until week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
Family therapy may leads to higher remission post‐intervention compared with standard care/treatment (low certainty).
It is very uncertain whether family therapy changes remission post‐intervention compared with psychological interventions (very low certainty).
It is very uncertain whether family therapy changes remission at long‐term compared with educational interventions (very low certainty).
Neoadjuvant chemotherapy prior to interval surgery (NACT) showed no clear difference in overall survival ( compared with surgery followed by chemotherapy (PDS) (high certainty).
Neoadjuvant chemotherapy prior to interval surgery (NACT) showed no clear difference in progression‐free survival ( compared with surgery followed by chemotherapy (PDS) (moderate certainty).