Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)

Intradialytic hypotension · chronic HD

Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic hypotension compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).

1 finding from 1 review

Low molecular weight heparin vs no LMWH

Incidence of compromised microcirculation requiring invasive intervention (re‐exploration) (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin (LMWH) changes incidence of compromised microcirculation requiring invasive… compared with no LMWH (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs no LMWH

Incidence of compromised microcirculation requiring invasive intervention (incision) (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin (LMWH) changes incidence of compromised microcirculation requiring invasive… compared with no LMWH (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs no LMWH

Microvascular insufficiency due to vessel occlusion ‐ arterial occlusion (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin (LMWH) changes microvascular insufficiency due to vessel occlusion ‐ arterial… compared with no LMWH (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs no LMWH

Microvascular insufficiency due to vessel occlusion ‐ venous occlusion (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin (LMWH) changes microvascular insufficiency due to vessel occlusion ‐ venous… compared with no LMWH (very low certainty).

1 finding from 1 review

Low molecular weight heparin vs no LMWH

Success rate of replantation1 (analysed by digit, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin (LMWH) changes success rate of replantation1 (analysed by digit, compared with no LMWH (very low certainty).

1 finding from 1 review