Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

920 questions · 964 findings · 153 reviews

No studies found 215 · 22.3%GRADE not reported 85 · 8.8%Very low 241 · 25%Low 260 · 27%Moderate 135 · 14%High 28 · 2.9%

Lithium vs lamotrigine

Efficacy: response (continuous) change in BPRS (total) from baseline to end of study ‐all data · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 301 participants
    Moderate

Lithium vs placebo

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania
1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 935 participants
    High