Heart failure hospitalisation (RR) · CVD (ASCVD, HF, or both)
DPP4i showed no clear difference in hospitalisation for HF compared with placebo (moderate certainty).
1 finding from 1 review
Worsening kidney function · CVD (ASCVD, HF, or both)
DPP4i showed no clear difference in worsening renal function compared with placebo (low certainty).
1 finding from 1 review
Hypoglycaemia · CVD (ASCVD, HF, or both)
DPP4i showed no clear difference in hypoglycaemia compared with placebo (moderate certainty).
1 finding from 1 review
Pancreatitis · CVD (ASCVD, HF, or both)
DPP4i probably leads to higher pancreatitis compared with placebo (moderate certainty).
1 finding from 1 review
Fracture · CVD (ASCVD, HF, or both)
DPP4i showed no clear difference in fracture compared with placebo (moderate certainty).
1 finding from 1 review
Repetition of SH at post‐intervention · self‐harm in children and adolescents (up to 18 years or age)
Comparison 7: Family therapy showed no clear difference in repetition of SH at post‐intervention compared with placebo (moderate certainty).
1 finding from 1 review
Repetition of SH at post‐intervention · self‐harm in adults
Antipsychotics may leads to lower repetition of SH by post‐intervention№ of participants: 30(1 RCT) compared with placebo (low certainty).
1 finding from 1 review
OR 0.09 [0.02, 0.5]
Studies not reported
Low
Repetition of SH at post‐intervention · self‐harm in adults
It is very uncertain whether mood stabilisers, including antiepileptics and lithium changes repetition of SH by post‐intervention№ of participants: 167(1 RCT) compared with placebo (very low certainty).
1 finding from 1 review
OR 0.99 [0.33, 2.95]
Studies not reported
Very low
Repetition of SH at post‐intervention · self‐harm in adults
Natural products showed no clear difference in repetition of SH by post‐intervention№ of participants: 49(1 RCT) compared with placebo (low certainty).
1 finding from 1 review
OR 1.33 [0.38, 4.62]
Studies not reported
Low
Subjective improvement in symptoms at 1 month and 3 months · adult participants with chronic blepharitis
1 finding from 1 review
Measurements of eradication or decrease in numbers of colonies of positive cultures of bacteria · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical signs—Schirmer test scores at 1 month (mm/5 min) · adult participants with chronic blepharitis
1 finding from 1 review
Clinical signs—TBUT at 1 month (seconds) · adult participants with chronic blepharitis
1 finding from 1 review
Adverse events at 1 month · adult participants with chronic blepharitis
It is very uncertain whether oral antibiotics changes adverse events at 1 month compared with placebo (very low certainty).
1 finding from 1 review
Quality of life measures · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Economic costs and benefits of different interventions · adult participants with chronic blepharitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total studies: 9 Total participants: 1757
1 finding from 1 review
no estimate extracted
9 participants
GRADE not reported
Dactolisib (1 RCT; 62 participants)
It is very uncertain whether estimates of effects, ranking, and certainty of evidence for… changes dactolisib (1 RCT; 62 participants) compared with placebo (very low certainty).
2 findings from 1 review
Total studies: 10 Total participants: 2113
1 finding from 1 review
no estimate extracted
10 participants
GRADE not reported
Everolimus
Estimates of effects, ranking, and certainty of evidence for… probably leads to lower everolimus (3 RCT; 632 participants) compared with placebo (moderate certainty).
4 findings from 1 review
HR 0.36 [0.28, 0.46]
3 studies · 632 participants
Moderate
OR 3.29 [2.21, 4.9]
3 studies · 632 participants
Moderate
OR 2.53 [0.95, 6.79]
1 study · 302 participants
Very low
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