Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Secondary alveolar bone grafting with a given sequence of orthodontic treatment (e.g. orthodontics before grafting) vs Secondary alveolar bone grafting with a different sequence of orthodontic treatment (e.g. orthodontics after grafting)

Outcome not reported · Patients greater than 5 years of age with unilateral or bilateral cleft lip and/or palate involving the alveolar process (complete or…

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs Topical fluoride (fluoride rinse, varnish or toothpaste)

Fluorosis (adverse effect; % of children with fluorotic teeth) · Children and adolescents aged 16 years or less

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs No fluoride supplement (placebo or no treatment)

Caries increment in permanent teeth · Children and adolescents aged 16 years or less
2 findings from 1 review

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Radiographic assessment: coronal bone volume (cm3) · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue led to higher radiographic assessment: coronal bone volume (cm3) compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Wound infection · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue showed no clear difference in postoperative complication: wound infection compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs Topical fluoride (fluoride rinse, varnish or toothpaste)

Plaque and gingivitis scores · Children and adolescents aged 16 years or less
1 finding from 1 review

Traditional iliac bone graft plus fibrin glue vs Traditional iliac bone graft alone

Radiographic assessment: coronal bone density (Hounsfield units) · Patients aged 7 to 16 years with unilateral or bilateral cleft lip and palate (alveolar cleft)

Traditional iliac bone graft plus fibrin glue led to higher radiographic assessment: coronal bone density (Hounsfield units) compared with traditional iliac bone graft alone; GRADE not reported.

1 finding from 1 review

Synbiotic vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether synbiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review

Probiotics vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review