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What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

Functional ability · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… showed no clear difference in functional status (mRS 0‐2) compared with avoiding anticoagulation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

MACE · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… probably leads to lower MACE (MACE) compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

Death · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… showed no clear difference in death compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

All major occlusive vascular events · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… probably leads to lower all major occlusive vascular events compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Starting long‐term therapeutic dose oral anticoagulation vs avoiding anticoagulation

Intracranial haemorrhage · survivors of stroke due to intracerebral haemorrhage with atrial fibrillation

Summary of findings table ‐ Starting long‐term therapeutic dose oral… showed no clear difference in intracranial haemorrhage compared with avoiding anticoagulation (moderate certainty).

1 finding from 1 review

Summary of findings for spaced retrieval training programme for people with dementia vs no intervention

Nutritional status · people with dementia
2 findings from 1 review

Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception

All‐cause mortality · people with COVID‐19

It is very uncertain whether summary of findings table ‐ Combined hormonal contraception… changes mortality compared with no contraception (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined hormonal contraception (estrogen plus progestin) vs no contraception

Hospitalization · people with COVID‐19

It is very uncertain whether summary of findings table ‐ Combined hormonal contraception… changes hospitalization compared with no contraception (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs mechanical bowel preparation alone

Surgical site infection · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… probably leads to lower SSI compared with mechanical bowel preparation alone (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Surgical site infection · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in surgical site infections compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Anastomotic leakage · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

All‐cause mortality · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with no bowel preparation (low certainty).

1 finding from 1 review