Norethisterone vs placebo
- Treatments for seizures in catamenial (menstrual‐related) epilepsy 2021 · Cochrane Headline outcomes onlyno estimate extracted24 participantsVery low
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The review found no eligible studies for this question.
Progesterone showed no clear difference in seizure freedom: all seizures compared with placebo (low certainty).
Progesterone showed no clear difference in responder rate: 50% or greater reduction in all seizures compared with placebo (moderate certainty).
Rapid susceptibility methods showed no clear difference in mortality compared with standard methods versus placebo (low certainty).
Rapid susceptibility methods showed no clear difference in mortality (subgroup genotypic) compared with standard methods versus placebo (low certainty).
Rapid susceptibility methods showed no clear difference in mortality (subgroup phenotypic) compared with standard methods versus placebo (low certainty).
Rapid susceptibility methods showed no clear difference in mortality (with stewardship) compared with standard methods versus placebo (low certainty).
Rapid susceptibility methods showed no clear difference in mortality (without stewardship) compared with standard methods versus placebo (low certainty).
It is very uncertain whether intravenous ketorolac changes number of participants with at least 50% pain relief over 4 hours compared with placebo (very low certainty).
Intravenous ketorolac may leads to higher number of participants with at least 50% pain relief over 6 hours compared with placebo (low certainty).
It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with placebo (very low certainty).
Intravenous ketorolac showed no clear difference in number of participants reporting any adverse event compared with placebo (moderate certainty).
Intravenous ketorolac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).
It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty).