Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Imiquimod vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Imiquimod probably leads to higher recurrence at 3 years compared with surgical excision (moderate certainty).

2 findings from 1 review

Imiquimod vs surgical excision

Number of patients with moderate/severe pain (1 hour postoperatively) · adults with basal cell carcinoma of the skin

Imiquimod showed no clear difference in pain (moderate/severe) compared with surgical excision (low certainty).

1 finding from 1 review

Psychological therapy vs usual care or attention control

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether psychological therapy changes adverse events: death ‐ at end of treatment (Analysis 2.16) compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Oral care interventions (nurse-assisted toothbrushing, oral and pharyngeal cavity rinse, decontamination with antibiotics or antiseptics) vs placebo

Presence of related infection: pneumonia · people with stroke

Oral health care intervention showed no clear difference in presence of related infection: pneumonia (Analysis 2.1) compared with placebo (low certainty).

1 finding from 1 review