Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,730 questions · 18,059 findings · 1,282 reviews

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Endovenous laser ablation (EVLA) vs foam sclerotherapy

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).

2 findings from 1 review

Nicotine replacement therapy vs placebo

Change in weight (kg) · People who have quit smoking

Nicotine replacement therapy for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (moderate certainty).

3 findings from 1 review

Varenicline vs placebo

Change in weight (kg) · People who have quit smoking

Varenicline for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (high certainty).

3 findings from 1 review

Fluoexetine vs placebo

Change in weight (kg) · People who have quit smoking

Fluoexetine showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (low certainty).

2 findings from 1 review

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

Complete recovery of facial nerve function at 12 months Defined as: complete recovery HB grade I. · Bell's palsy

It is very uncertain whether surgery for Bell's palsy changes complete recovery of facial nerve function at 12 months Defined as:… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

1 finding from 1 review

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

Complications and side effects · Bell's palsy

It is very uncertain whether surgery for Bell's palsy changes side effects and complications of treatmentMeasured by clinical… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

1 finding from 1 review

Early surgery vs late surgery

Complete recovery of facial nerve function at 12 months Defined as: complete recovery HB grade I. · Bell's palsy

It is very uncertain whether early surgery changes complete recovery of facial nerve function at 12 months Defined as:… compared with late surgery (very low certainty).

1 finding from 1 review