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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Other dressing vs control
Pressure ulcer incidence: adhesive foam dressing vs no dressing · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 1.65 [1.1, 2.48]1 study · 78 participantsVery low
Other dressing vs control
Adverse events · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Fatty acid vs other topical intervention or standard care
Pressure ulcer incidence: fatty acid vs standard care · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 0.7 [0.41, 1.18]2 studies · 187 participantsLow
Fatty acid vs other topical intervention or standard care
Pressure ulcer incidence: fatty acid vs olive oil (high‐quality trials) · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 1.46 [0.77, 2.75]1 study · 831 participantsLow
Fatty acid vs other topical intervention or standard care
Adverse event: fatty acid vs olive oil · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 2.22 [0.2, 24.37]1 study · 831 participantsLow
Active topical agent vs placebo/control
Pressure ulcer incidence: active lotion vs placebo · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 0.73 [0.45, 1.19]1 study · 167 participantsVery low
Active topical agent vs placebo/control
Pressure ulcer incidence: DMSO cream vs placebo · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 1.99 [1.1, 3.57]1 study · 61 participantsLow
Active topical agent vs placebo/control
Pressure ulcer incidence: Conotrane vs placebo · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 0.74 [0.52, 1.07]1 study · 258 participantsVery low
Active topical agent vs placebo/control
Pressure ulcer incidence: Prevasore vs control · individuals at risk of pressure ulcer development
Dressings and topical agents for preventing pressure ulcers (2018) · Cochrane
RR 0.33 [0.04, 3.11]1 study · 120 participantsVery low
Profiling bed with foam mattress vs hospital bed with foam mattress
Pressure ulcer healing · patients from two surgical and two medical wards
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 3.96 [1.28, 12.24]1 study · 70 participantsVery low
Alternating‐pressure cushion vs dry flotation cushion
Pressure ulcers completely healed · patients with pressure ulcers
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.47 [0.14, 1.56]1 study · 25 participantsLow
Water mattress overlay vs low‐tech mattress
Pressure ulcer healing · nursing home patients, > 59 years old
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.93 [0.63, 1.37]1 study · 120 participantsLow
Low‐air‐loss bed vs low‐tech mattress overlay
Pressure ulcers completely healed · elderly nursing home residents with multiple medical problems
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 1.3 [0.87, 1.96]1 study · 84 participantsLow
Intervention NR
Ulcers completely healed · varied
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.57 [0.26, 1.27]1 study · 30 participantsLow
Intervention NR
Decrease in pressure ulcer size · varied
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.58 [0.21, 1.65]1 study · 30 participantsLow
Intervention NR
Ulcers completely healed · varied
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.99 [0.9, 1.09]1 study · 141 participantsLow
Alternating‐pressure mattress vs alternating‐pressure mattress overlay
Pressure ulcer improvement · varied
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.97 [0.8, 1.17]1 study · 158 participantsLow
Alternating‐pressure mattress vs alternating‐pressure mattress overlay
Pressure ulcer healing · varied
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 0.96 [0.58, 1.6]1 study · 113 participantsLow
Alternating‐pressure mattress vs air‐filled devices
Proportion of patients with healed pressure ulcer · patients with pressure ulcers
Support surfaces for treating pressure ulcers (2018) · Cochrane
RR 5.5 [0.73, 41.44]1 study · 50 participantsLow
NPWT vs dressings
Proportion of wounds healed · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 1.44 [1.03, 2.01]1 study · 162 participantsLow
NPWT vs dressings
Amputations · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 0.33 [0.15, 0.7]3 studies · 441 participantsLow
NPWT vs dressings
Number of wounds closed or covered with surgery · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 1.02 [0.85, 1.24]3 studies · 129 participantsLow
NPWT vs dressings
Adverse events · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Wound recurrence · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 0.5 [0.1, 2.53]1 study · 60 participantsVery low
Low‐pressure vs high‐pressure NPWT
Proportion of wounds healed · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Time to ulcer healing · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Amputation · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Number of wounds closed or covered with surgery · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 0.83 [0.47, 1.47]1 study · 40 participantsVery low
Low‐pressure vs high‐pressure NPWT
Adverse events · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 1.5 [0.28, 8.04]1 study · 40 participantsVery low
NPWT vs dressings
Time to healing · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
HR 1.91 [1.21, 2.99]1 study · 162 participantsLow
Low‐pressure vs high‐pressure NPWT
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
Low‐pressure vs high‐pressure NPWT
Wound recurrence · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Amputations · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 0.38 [0.14, 1.02]2 studies · 292 participantsVery low
NPWT vs dressings
Number of wounds closed or covered with surgery · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 1.02 [0.95, 1.09]1 study · 130 participantsVery low
NPWT vs dressings
Adverse events · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 0.96 [0.72, 1.28]1 study · 162 participantsVery low
NPWT vs dressings
Cost‐effectiveness · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Wound recurrence · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extractedNRNo studies
NPWT vs dressings
Proportion of wounds healed · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
RR 1.4 [1.14, 1.72]5 studies · 486 participantsLow
NPWT vs dressings
Time to healing · treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus (2018) · Cochrane
no estimate extracted3 studies · 468 participantsLow
Education vs no education
Knowledge in hospital group · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extracted1 study · 10 participantsVery low
Training, monitoring and observation vs monitoring and observation
Incidence of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
RR 0.63 [0.37, 1.05]1 study · 345 participantsVery low
Training, monitoring and observation vs monitoring and observation
Severity of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs monitoring and observation
Patient‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs monitoring and observation
Carer‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Change in health professionals' knowledge · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Change in health professionals' clinical behaviour · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Incidence of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
RR 1.21 [0.6, 2.43]1 study · 325 participantsVery low
Training, monitoring and observation vs observation alone
Severity of new pressure ulcers · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies
Training, monitoring and observation vs observation alone
Patient‐reported outcomes · staff caring for patients at risk of pressure ulcers
Education of healthcare professionals for preventing pressure ulcers (2018) · Cochrane
no estimate extractedNRNo studies