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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,751 questions in 147 reviews · Pain, Palliative and Supportive Care

current versions
No studies 361 · 20.6%Ungraded 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Dexamethasone vs placebo
Nausea at 8 days Scale from: 0 to 10; lower score = less nausea. · participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to… (2017) · Cochrane
no estimate extracted2 studies · 127 participantsVery low
Dexamethasone vs placebo
Number of vomiting episodes · participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to… (2017) · Cochrane
no estimate extractedNRNo studies
Dexamethasone vs placebo
Adverse events · participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to… (2017) · Cochrane
no estimate extractedNRNo studies
Dexamethasone vs placebo
Quality of life · participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to… (2017) · Cochrane
no estimate extractedNRNo studies
Dexamethasone vs placebo
Patient satisfaction · participants with advanced cancer who have nausea and vomiting not related to chemotherapy, radiotherapy, or surgery
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to… (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Fatigue · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
no estimate extracted12 studies · 535 participantsVery low
Intervention NR
Physical functioning · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
SMD 0.327 studies · 307 participantsVery low
Intervention NR
Social functioning · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
MD 4.164 studies · 141 participantsVery low
Intervention NR
Role functioning · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
MD 3.494 studies · 143 participantsVery low
Intervention NR
Emotional functioning · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
no estimate extracted3 studies · 115 participantsVery low
Intervention NR
Cognitive functioning · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
no estimate extracted2 studies · 86 participantsVery low
Intervention NR
Adverse events · patients with incurable cancer receiving cancer treatment with palliative intent
Psychosocial interventions for fatigue during cancer treatment with palliative intent (2017) · Cochrane
no estimate extractedNRNo studies
CBT with biofeedback ± physical exercise vs waiting list control
Pain relief At least 30% pain relief or pain < 5/10 Scales: VRS 0‐6; SFMPQ‐PRI (0‐45) · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extracted2 studies · 58 participantsVery low
CBT with biofeedback ± physical exercise vs waiting list control
Adverse effects, including dropout and attrition · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extractedNRNo studies
CBT with biofeedback ± physical exercise vs waiting list control
Reduced use of analgesics · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extractedNRNo studies
CBT with biofeedback ± physical exercise vs waiting list control
Reduction in disability Pain Coping Questionnaire behavioural subscale (12 items: 0‐7); WHODAS‐II (12 items: 1‐5) · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extracted2 studies · 57 participantsVery low
CBT with biofeedback ± physical exercise vs waiting list control
Quality of life · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extractedNRNo studies
CBT with biofeedback ± physical exercise vs waiting list control
Reduction in distress PDS (17 items: 0‐3) HTQ‐Part IV (30 items: 1‐4) · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extracted2 studies · 58 participantsVery low
CBT with biofeedback ± physical exercise vs waiting list control
Global improvement, satisfaction · adult torture survivors with chronic pain
Interventions for treating persistent pain in survivors of torture (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extracted1 study · 45 participantsVery low
Acupuncture vs other active therapy
Participant‐reported pain relief · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs other active therapy
Participants experiencing any serious adverse event · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs other active therapy
Quality of life · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture combined with other active therapy vs other active therapy
Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extracted1 study · 104 participantsVery low
Acupuncture combined with other active therapy vs other active therapy
Participant‐reported pain relief substantial (at least 50% pain relief over baseline) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture combined with other active therapy vs other active therapy
Participants experiencing any serious adverse event · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture combined with other active therapy vs other active therapy
Quality of life FACT/the GOG‐Ntx questionnaire scores (0 ‐ 100, lower score = better) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extracted1 study · 104 participantsLow
Acupuncture vs sham acupuncture
Participant‐reported pain relief substantial (at least 50% pain relief over baseline) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Participants experiencing any serious adverse event · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Quality of life SF‐36 bodily pain score (0‐100, lower score = more disability) · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extracted1 study · 45 participantsVery low
Acupuncture vs treatment
Participant‐reported pain intensity · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs treatment
Participant‐reported pain relief · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs treatment
Participants experiencing any serious adverse event · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs treatment
Quality of life · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs other active therapy
Participant‐reported pain intensity · adults with neuropathic pain
Acupuncture for neuropathic pain in adults (2017) · Cochrane
no estimate extractedNRNo studies
TENS vs placebo TENS
Participant‐reported pain relief ≥ 30% (≥ 30% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs no treatment
Withdrawals due to adverse events · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS with exercise vs exercise alone
Participant‐reported pain relief ≥ 30% (≥ 30% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extracted1 study · 28 participantsVery low
TENS with exercise vs exercise alone
Participant‐reported pain relief ≥ 50% (≥ 50% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS with exercise vs exercise alone
PGIC much or very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS with exercise vs exercise alone
PGIC very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS with exercise vs exercise alone
Withdrawals due to adverse events · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs other active treatment
Participant‐reported pain relief ≥ 30% (≥ 30% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs other active treatment
Participant‐reported pain relief ≥ 50% (≥ 50% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs other active treatment
PGIC much or very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs other active treatment
PGIC very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs placebo TENS
Participant‐reported pain relief ≥ 50% (≥ 50% pain relief) · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs other active treatment
Withdrawals due to adverse events · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs placebo TENS
PGIC very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low
TENS vs placebo TENS
PGIC much or very much improved · adults with fibromyalgia
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults (2017) · Cochrane
no estimate extractedNRVery low