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Evidence found and GRADE certainty

461 questions · 473 findings · 36 reviews · HIV/AIDS

No studies found 38 · 8%GRADE not reported 9 · 1.9%Very low 126 · 26.6%Low 127 · 26.8%Moderate 152 · 32.1%High 21 · 4.4%

Bae: AZT/3TC/NVP vs Other Short Course PMTCT Regimen

Mother to Child Transmission at 12 Months · ART‐Eligible HIV‐infected Pregnant Women

It is very uncertain whether ekouevi: AZT/3TC/NVP changes mother to Child Transmission at 12 Months compared with other Short Course PMTCT Regimen (very low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs >250 cells/mm3

Hepatotoxicity:13 Grade 3 and 4 toxicity · HIV‐infected pregnant women

Marazzi: AZT/3TC/NVP for HIV Infection in Pregnant Women With CD4 <250 showed no clear difference in maternal Grade 3/4 Hepatotoxicity compared with >250 cells/mm3; GRADE not reported.

1 finding from 1 review

Bae: AZT/3TC/NVP vs AZT/3TC/NVP

Maternal Grade 3/4 Severe Adverse Events · HIV‐1 Infected Pregnant Women Who Have CD4>200 Compared with Those Who Have CD4<200 Cells/mm3

It is very uncertain whether phanuphak: AZT/3TC/NVP (PMTCT) changes maternal Grade 3/4 Severe Adverse Events compared with AZT/3TC/NVP (ART) (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Mortality at 12 months · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora: AZT/3TC/LPV‐r showed no clear difference in infant Mortality at 12 months compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Maternal Grade 3/4 Severe Adverse Events Requiring Treatment Modification · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold: AZT/3TC/NVP changes maternal Grade 3/4 Severe Adverse Events Requiring Treatment… compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Mother to Child Transmission at 1 Month · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold continued: AZT/3TC/NVP changes mother to Child Transmission of HIV at 1 Month compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Bae: AZT/3TC/NVP vs Other Short Course Regimen

Mother to Child Transmission at 12 Months · HIV‐infected pregnant women

It is very uncertain whether tonwe‐Gold continued: AZT/3TC/NVP changes mother to Child Transmission of HIV at 12 Months compared with other Short Course Regimen (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Maternal Grade 3/4 Severe Adverse Events · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

It is very uncertain whether kesho Bora: AZT/3TC/LPV‐r changes maternal Grade 3/4 Severe Adverse Events compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Grade 3/4 Severe Adverse Events · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora: AZT/3TC/LPV‐r showed no clear difference in infant Grade 3/4 Severe Adverse Events compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Prematurity · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

It is very uncertain whether kesho Bora: AZT/3TC/LPV‐r changes prematurity compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (very low certainty).

1 finding from 1 review

Kesho Bora: AZT/3TC/LPV‐r vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Low birthweight · HIV‐infected Pregnant Women With CD4 Counts 200‐500 Cells/mm3

Kesho Bora continued: AZT/3TC/LPV‐r showed no clear difference in low Birth Weight compared with short‐Course AZT (intrapartum AZT/3TC/sd‐NVP) (low certainty).

1 finding from 1 review