Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

761 questions · 801 findings · 50 reviews · Common Mental Disorders

No studies found 125 · 15.6%GRADE not reported 34 · 4.2%Very low 226 · 28.2%Low 232 · 29%Moderate 176 · 22%High 8 · 1%

TCAs with predominantly SRI actions vs placebo

Dropouts due to adverse events · adults with trichotillomania

It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).

1 finding from 1 review

Antioxidants vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · children with trichotillomania

Antioxidants showed no clear difference in treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (low certainty).

1 finding from 1 review

Antioxidants vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · children with trichotillomania
1 finding from 1 review

Antipsychotics vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with trichotillomania

Antipsychotics may leads to higher treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ cognitive function ‐ immediate memory (high = better; short term) · patients with schizophrenia
1 finding from 1 review

Intervention not reported

MST vs ECT ‐ cognitive function ‐ delayed memory (high = better; short term) · patients with schizophrenia
1 finding from 1 review

Intervention not reported

MST vs ECT ‐ suicides, suicide attempts, self‐harm · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ social functioning · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ dropout for any reason (short term) · patients with schizophrenia

It is very uncertain whether the intervention changes MST vs ECT ‐ dropout for any reason (short term) (very low certainty).

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ serious adverse events · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

MST vs ECT ‐ adverse events that led to discontinuation of treatment (short term) · patients with schizophrenia
1 finding from 1 review