Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

460 questions · 475 findings · 36 reviews · Developmental, Psychosocial and Learning Problems

No studies found 153 · 32.2%GRADE not reported 18 · 3.8%Very low 177 · 37.3%Low 86 · 18.1%Moderate 40 · 8.4%High 1 · 0.2%

Probiotics vs placebo

Improvement in pain: 0 to 3 months' postintervention Subgroup (irritable bowel syndrome) Different measures were used to assess improvement in pain, as above. · Children with recurrent abdominal pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Subgroup… compared with placebo (moderate certainty).

1 finding from 1 review