What do systematic reviews say?

Embryo culture supernatant vs culture medium injection

It is very uncertain whether embryo culture supernatant changes clinical pregnancy compared with culture medium injection (very low certainty).

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  OR 1.09 [0.48, 2.46]
  1 study · 96 participants
  Very low

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Embryo culture supernatant vs culture medium injection

The review found no eligible studies for this question.

• Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Double vs single‐injection technique

Double leads to lower primary anaesthesia failure (incomplete sensory block) compared with single‐injection technique (high certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.55 [0.34, 0.89]
  9 studies · 527 participants
  High

Multiple vs single‐injection technique

Multiple showed no clear difference in secondary analgesia failure ‐ tourniquet pain compared with single‐injection technique (high certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.97 [0.3, 3.11]
  4 studies · 379 participants
  High

Multiple vs single‐injection technique

Multiple showed no clear difference in complete failure of block1 compared with single‐injection technique (moderate certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.31 [0.03, 2.71]
  7 studies · 484 participants
  Moderate

Multiple vs single‐injection technique

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 206 participants
  Low

Multiple vs single‐injection technique

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 244 participants
  Low

Multiple vs double‐injection technique

Multiple leads to lower primary anaesthesia failure compared with double‐injection technique (high certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.27 [0.19, 0.39]
  12 studies · 966 participants
  High

Multiple vs double‐injection technique

Multiple showed no clear difference in secondary analgesia failure ‐ intraoperative sedation required compared with double‐injection technique (high certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.75 [0.55, 1.03]
  7 studies · 716 participants
  High

Multiple vs double‐injection technique

Multiple leads to lower secondary analgesia failure ‐ tourniquet pain compared with double‐injection technique (high certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.53 [0.33, 0.84]
  7 studies · 719 participants
  High

Multiple vs double‐injection technique

Multiple showed no clear difference in complete failure of block1 compared with double‐injection technique (low certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.24 [0.04, 1.41]
  9 studies · 630 participants
  Low

Multiple vs double‐injection technique

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 524 participants
  Moderate

Double vs single‐injection technique

Double showed no clear difference in secondary analgesia failure ‐ intraoperative sedation required compared with single‐injection technique (moderate certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.64 [0.31, 1.31]
  2 studies · 129 participants
  Moderate

Multiple vs double‐injection technique

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 510 participants
  Low

Double vs single‐injection technique

Double showed no clear difference in secondary analgesia failure ‐ tourniquet pain compared with single‐injection technique (moderate certainty).

• Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults… 2016 · Cochrane Headline outcomes only
  RR 0.58 [0.22, 1.52]
  2 studies · 104 participants
  Moderate