Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

Oral vs topical antibiotics

Active trachoma · people (any age) with active trachoma

Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).

1 finding from 1 review

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Intervention not reported

Change in function Health Assessment Questionnaire (HAQ) at 12 weeks (0 to 3 score; lower score means better function) · people with rheumatoid arthritis

It is very uncertain whether the intervention changes change in function Health Assessment Questionnaire (HAQ) at 12 weeks… (very low certainty).

1 finding from 1 review

IVIg vs placebo

Global assessment · patients with drug‐resistant epilepsy

IVIg may leads to higher global assessment compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Caregiver physical health status Studies (reported in comments section): Multilevel Assessment Instrument Total Score (Budin 2008).*** SF12 Physcial Component Summary Score (Northouse 2007). Higher scores indicate higher levels of physical health ... · informal caregivers of people affected by cancer

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

HSS (hypersensitivity) reaction including SJS/TEN (clinically diagnosed) (6 weeks clinical assessment) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The intervention probably leads to lower HSS (hypersensitivity) reaction including SJS/TEN (clinically… (moderate certainty).

1 finding from 1 review

Intervention not reported

HSS reaction including SJS/TEN (immunologically confirmed) (6 weeks clinical assessment) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The intervention probably leads to lower HSS reaction including SJS/TEN (immunologically confirmed) (6 weeks… (moderate certainty).

1 finding from 1 review