Recurrence · people with GSV incompetence
Radiofrequency ablation (RFA) showed no clear difference in recurrence (< 5 years) compared with SFJ ligation and stripping (HL/S) (moderate certainty).
1 finding from 1 review
Long‐term recurrence (> 5 years) · people with GSV incompetence
Radiofrequency ablation (RFA) may leads to lower long‐term recurrence (> 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).
1 finding from 1 review
Complications (up to 8 years) · people with GSV incompetence
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Recurrence · people with GSV incompetence
Endovenous laser ablation (EVLA) showed no clear difference in recurrence (< 5 years) compared with radiofrequency ablation (RFA) (low certainty).
1 finding from 1 review
QoL · people with GSV incompetence
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Technical success · people with GSV incompetence
Ultrasound‐guided foam sclerotherapy (UGFS) may leads to lower technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).
2 findings from 1 review
Recurrence · people with GSV incompetence
Ultrasound‐guided foam sclerotherapy (UGFS) showed no clear difference in recurrence (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).
1 finding from 1 review
Long‐term recurrence (> 5 years) · people with GSV incompetence
Ultrasound‐guided foam sclerotherapy (UGFS) showed no clear difference in long‐term recurrence (≥ 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).
1 finding from 1 review
Complications (up to 8 years) · people with GSV incompetence
1 finding from 1 review
QoL · people with GSV incompetence
1 finding from 1 review
Long‐term recurrence (> 5 years) · people with GSV incompetence
Endovenous laser ablation (EVLA) may leads to higher long‐term recurrence (> 5 years) compared with radiofrequency ablation (RFA) (low certainty).
1 finding from 1 review
Complications (up to 8 years) · people with GSV incompetence
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
QoL · people with GSV incompetence
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Technical success · people with GSV incompetence
Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).
2 findings from 1 review
Recurrence · people with GSV incompetence
It is very uncertain whether endovenous laser ablation (EVLA) changes recurrence (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (very low certainty).
1 finding from 1 review
Change in weight (kg) · People who have quit smoking
Nicotine replacement therapy for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (moderate certainty).
3 findings from 1 review
MD 0.52
21 studies · 2784 participants
Moderate
MD 0.08
11 studies · 1021 participants
Moderate
MD 0.37
17 studies · 1463 participants
Moderate
Change in weight (kg) · People who have quit smoking
Varenicline for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (high certainty).
3 findings from 1 review
MD 0.23
14 studies · 2566 participants
High
MD 0.09
3 studies · 384 participants
Low
MD 1.05
3 studies · 237 participants
Low
Change in weight (kg) · People who have quit smoking
Fluoexetine showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (low certainty).
2 findings from 1 review
Intervention not reported
Clinical outcomes · Adults with multimorbidity (two or more chronic conditions)
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Mental health outcomes · Adults with multimorbidity (two or more chronic conditions)
1 finding from 1 review
no estimate extracted
Studies not reported
High