Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 17,858 findings · 1,266 reviews

No studies found 4,359 · 24.4%GRADE not reported 2,348 · 13.1%Very low 4,634 · 25.9%Low 4,000 · 22.4%Moderate 2,052 · 11.5%High 465 · 2.6%

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Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Motor alignment at distance Change in exotropia control at near fixation, measured from baseline to 3 years using the prism and alternate cover test · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in motor alignment at distance Change in exotropia control at near… compared with unilateral lateral rectus recession with medial rectus resection (moderate certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged 3 to < 11 years
1 finding from 1 review

Patching vs active observation

Motor alignment at near fixation Measured using PACT at 6 months · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in motor alignment at near fixation Measured using PACT at 6 months compared with active observation (high certainty).

1 finding from 1 review

Patching vs active observation

Stereoacuity at near · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in stereoacuity at near Measured using the Preschool Randot, Titmus… compared with active observation (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs radiofrequency ablation

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with radiofrequency ablation (RFA) (moderate certainty).

2 findings from 1 review

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) may leads to higher technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review

Radiofrequency ablation (RFA) vs mechanochemical ablation (MOCA)

Technical success · people with GSV incompetence

Radiofrequency ablation (RFA) showed no clear difference in technical success (< 5 years) compared with mechanochemical ablation (MOCA) (low certainty).

2 findings from 1 review

Radiofrequency ablation (RFA) vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Radiofrequency ablation (RFA) showed no clear difference in technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review