Extraoral masticatory muscle tenderness (number of tender sites), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in extraoral masticatory muscle tenderness (number of tender sites),… compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Pain score · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Vitamin B12 (sublingual, 1000 mcg daily for 6 months) led to lower pain score compared with placebo; GRADE not reported.
1 finding from 1 review
Decrease in duration of attacks · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Levamisole (150 mg per day) showed no clear difference in decrease in duration of attacks compared with placebo; GRADE not reported.
1 finding from 1 review
RR 4.29 [0.67, 27.24]
1 study
GRADE not reported
Participant global self-assessment · People with erosive oral lichen planus
1 finding from 1 review
One study (Passeron 2007) assessed participant global self-assessment on a 5-point scale: 5/6 participants in the 1% pimecrolimus group rated their improvement as moderate or important versus 1/6 in the placebo group…
1 study · 12 participants
GRADE not reported
Laser therapy
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Overall effectiveness (days to resolution; number of aphthae per month) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
A comparison between sulodexide (n=10) and prednisone (n=10) was made in a trial at high risk of bias (Femiano 2003). Data presented as ranges/totals only with no estimate of variability, precluding further analysis.…
1 study · 20 participants
GRADE not reported
Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Diclofenac sodium (oral NSAID) showed no clear difference in complications (adverse effects) compared with occlusal splint therapy; GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis
Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing pocket depth (PPD) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.
1 finding from 1 review
Eating a normally varied diet · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions
The review found no eligible studies for this question.
1 finding from 1 review
Framework survival (5 years) · Patients with implant-supported FDPs; split-mouth, 5-year
1 finding from 1 review
95% (20/21) titanium and 100% cast gold frameworks surviving 5 years; could not calculate an estimate of relative risk from the data as presented; non-significant differences in maintenance visits and alveolar bone loss
1 study · 21 participants
GRADE not reported
Reported pain (mm on VAS), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in reported pain (mm on VAS), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Patient satisfaction · Partially edentulous patients treated with a distal-extension RDP
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain intensity, change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Adverse effects · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Complications and side effects · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Complete remission, pain intensity, patient and physician evaluation · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
One trial at high risk of bias (de Abreu 2009) compared clofazimine (n=23) with colchicine (n=23). The number with no further aphthous episodes at 6 months was significantly greater in the clofazimine group than the…
1 study · 46 participants
GRADE not reported
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Mean number of lesions over treatment period · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Bee propolis (one 500 mg capsule per day) showed no clear difference in mean number of lesions over treatment period compared with placebo; GRADE not reported.
1 finding from 1 review