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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

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No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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HALOPERIDOL vs chlorpromazine

Adverse events including extrapyramidal effects · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes adverse events including extrapyramidal effectsc compared with chlorpromazine (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes symptoms of delirium between 24 and 48 hoursa compared with lorazepam (very low certainty).

1 finding from 1 review

HALOPERIDOL vs lorazepam

Adverse events including extrapyramidal effects · terminally ill adults with delirium

It is very uncertain whether summary of findings: haloperidol changes adverse events including extrapyramidal effectsc compared with lorazepam (very low certainty).

1 finding from 1 review

HALOPERIDOL vs placebo

Adverse events including extrapyramidal effects · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in adverse events including extrapyramidal effectse compared with placebo (moderate certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Symptoms of delirium within 24 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium within 24 hoursa compared with risperidone (low certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Symptoms of delirium between 24 and 48 hoursa · terminally ill adults with delirium

Summary of findings: haloperidol showed no clear difference in symptoms of delirium between 24 and 48 hoursa compared with risperidone (low certainty).

1 finding from 1 review

Botulinum toxin type A vs placebo

Adverse events (reported at any time) (2 RCT, 169 participants) · adults with blepharospasm

Botulinum toxin type A showed no clear difference in adverse events (reported at any time) (2 RCT, 169 participants) compared with placebo (low certainty).

1 finding from 1 review

Botulinum toxin type A vs placebo

Tolerability (number of dropouts; reported at any time) (2 RCT, 169 participants) · adults with blepharospasm

Botulinum toxin type A showed no clear difference in tolerability (number of dropouts; reported at any time) (2 RCT, 169… compared with placebo (moderate certainty).

1 finding from 1 review