Overall survival (total mortality), chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
1 finding from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with allograft changes changes in vertical height of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).
1 finding from 1 review
Chemotherapy vs Placebo
Outcome not reported · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of successfully erupted PDC that were favourably positioned · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
Double primary (canine and first molar) tooth extraction showed no clear difference in incidence of successfully erupted PDC that were favourably positioned compared with single primary (canine) tooth extraction; GRADE not reported.
2 findings from 1 review
Any other adverse effects of the interventions, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
The review found no eligible studies for this question.
1 finding from 1 review
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Overall survival, induction platinum + 5-fluorouracil prior to radiotherapy vs radiotherapy alone · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… showed no clear difference in overall survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone (moderate certainty).
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with xenograft (bone graft) changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with demineralised bone matrix, single particle size changes changes in vertical height of alveolar ridge (mm) compared with ARP with demineralised bone matrix, multiple particle size (very low certainty).
1 finding from 1 review
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Disease-free survival · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Induction chemotherapy plus locoregional treatment (radiotherapy… led to lower disease-free survival, induction platinum + 5-fluorouracil prior to… compared with locoregional treatment (radiotherapy and/or surgery) alone; GRADE not reported.
1 finding from 1 review
Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review
1 trial (Cha 2019) reported delayed healing with partial exposure of the buccal plate at suture removal by 1 participant in the test group; another trial (Festa 2013) reported pain and swelling
2 studies · 54 participants
Low
Number of participants referred for surgical exposure of the PDC · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
It is very uncertain whether double primary (canine and first molar) tooth extraction changes number of participants referred for surgical exposure of the PDC compared with single primary (canine) tooth extraction (very low certainty).
1 finding from 1 review
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with xenograft (bone graft) changes implant failure rate compared with extraction alone (very low certainty).
1 finding from 1 review
Lesion progression · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with allograft plus synthetic cell-binding peptide P-15 changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with allograft without P-15 (very low certainty).
1 finding from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
Selective carious tissue removal (selective excavation, SE) probably leads to higher failure of therapy compared with stepwise carious tissue removal (SW) (moderate certainty).
1 finding from 1 review