What do systematic reviews say?

Maintenance anaesthesia: inhalational vs intravenous

Maintenance anaesthesia: inhalational may leads to higher nausea and vomiting ‐ subgroup analysis: thiopentone or halothane +… compared with intravenous (low certainty).

• Intravenous versus inhalational anaesthesia for paediatric outpatient surgery 2014 · Cochrane Headline outcomes only
  OR 3.23 [1.49, 7.02]
  4 studies · 176 participants
  Low
• Intravenous versus inhalational anaesthesia for paediatric outpatient surgery 2014 · Cochrane Headline outcomes only
  OR 7.44 [2.6, 21.26]
  2 studies · 87 participants
  Low

Intervention not reported

The intervention showed no clear difference in overall Survival (median (low certainty).

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  HR 1.11 [0.83, 1.48]
  5 studies · 663 participants
  Low

Intervention not reported

The intervention showed no clear difference in progression free survival (low certainty).

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  HR 0.76 [0.53, 1.1]
  2 studies · 378 participants
  Low

Intervention not reported

The intervention may leads to lower any intracranial disease progression at 1 year (low certainty).

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  RR 0.46 [0.35, 0.6]
  4 studies · 304 participants
  Low

Intervention not reported

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 209 participants
  Low

Intervention not reported

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 436 participants
  Low

Intervention not reported

• Surgery or radiosurgery plus whole brain radiotherapy versus surgery or radiosurgery alone for brain metastases 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 568 participants
  Low

Intervention not reported

The intervention probably leads to lower lymph node mets analysis ‐ N+ OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.78 [0.67, 0.91]
  4 studies · 877 participants
  Moderate

Intervention not reported

The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.88 [0.83, 0.94]
  28 studies · 5694 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in chemobased OS ‐ Platinum‐based chemotherapy OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.9 [0.81, 1]
  9 studies · 1504 participants
  Moderate

Intervention not reported

The intervention probably leads to lower chemobased DFS ‐ 5‐FU based chemotherapy DFS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.86 [0.78, 0.95]
  13 studies · 2944 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in chemobased DFS ‐ Platinum‐based chemotherapy DFS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.89 [0.75, 1.06]
  4 studies · 969 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in stage OS analysis ‐ T1/2 OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.86 [0.71, 1.05]
  5 studies · 1146 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in stage OS analysis ‐ T3/4 OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.66 [0.41, 1.08]
  4 studies · 1008 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in lymph node mets analysis ‐ N‐ OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.74 [0.41, 1.33]
  2 studies · 402 participants
  Moderate

Intervention not reported

The review found no eligible studies for this question.

• Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

It is very uncertain whether the intervention changes poor visual outcome (best‐corrected visual acuity worse than 6/60) (very low certainty).

• Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with… 2013 · Cochrane Headline outcomes only
  OR 2.48 [0.74, 8.28]
  6 studies · 1250 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found