Findings

What do systematic reviews say?

4,345 questions · 4,525 findings · 483 reviews

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No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Transanal repair vs transvaginal repair

Operating time · women with posterior vaginal wall prolapse

1 finding from 1 review

Surgery for women with posterior compartment prolapse 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 137 participants
Very low

Biological graft vs native tissue repair

Outcomes ( · women with posterior vaginal wall prolapse

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for women with posterior compartment prolapse 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

GnRHa treatment vs placebo or no pretreatment

Uterine volume (cm³) · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 858 participants
Low

GnRHa treatment vs placebo or no pretreatment

Intraoperative blood loss (mL) · women with uterine fibroids

3 findings from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 549 participants
Very low
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 258 participants
Very low

GnRHa treatment vs placebo or no pretreatment

Blood transfusion · women with uterine fibroids

GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.85 [0.26, 2.75]
4 studies · 121 participants
Low
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.54 [0.29, 1.01]
6 studies · 601 participants
Moderate

GnRHa treatment vs placebo or no pretreatment

Overall postoperative morbidity · women with uterine fibroids

GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 1.07 [0.43, 2.64]
5 studies · 190 participants
Low
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.54 [0.32, 0.91]
7 studies · 772 participants
Low

GnRHa treatment vs placebo or no pretreatment

Fibroid volume (cm³) · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 427 participants
Low

SPRM vs placebo

Uterine volume (cm³) · women with uterine fibroids

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SPRM vs placebo

Fibroid volume (cm³) · women with uterine fibroids

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SPRM vs placebo

Haemoglobin (g/dL) · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 173 participants
High

SPRM vs placebo

Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids

SPRM may leads to higher preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg compared with placebo (low certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 41.41 [15.26, 112.38]
1 study · 143 participants
Low

SPRM vs placebo

Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids

SPRM may leads to higher preoperative bleeding: Reduction in menstrual bleeding (PBAC < 75)… compared with placebo (low certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 78.83 [24.02, 258.74]
1 study · 146 participants
Low

SPRM vs placebo

Preoperative bleeding: Change in menstrual blood loss from baseline to end of treatment · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low

GnRHa treatment vs placebo or no pretreatment

Haemoglobin (g/dL) · women with uterine fibroids

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 834 participants
Low

SPRM vs placebo

Adverse events · women with uterine fibroids

SPRM showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 0.05 [0, 1]
1 study · 241 participants
Low

GnRHa treatment vs placebo or no pretreatment

Preoperative bleeding · women with uterine fibroids

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

GnRHa treatment vs placebo or no pretreatment

Adverse events · women with uterine fibroids

GnRHa treatment probably leads to higher adverse events compared with placebo or no pretreatment (preoperative outcomes) (moderate certainty).

1 finding from 1 review

Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
OR 2.78 [1.77, 4.36]
4 studies · 755 participants
Moderate

Intervention not reported

Early postoperative non‐thrombotic complications · Individuals with peripheral arterial disease

The intervention showed no clear difference in early postoperative non‐thrombotic complications (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.29 [0.96, 1.73]
6 studies · 1015 participants
High

Intervention not reported

Procedural mortality · Individuals with peripheral arterial disease

The intervention showed no clear difference in procedural mortality (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.67 [0.66, 4.19]
5 studies · 913 participants
High

Intervention not reported

Clinical improvement · Individuals with peripheral arterial disease

The intervention showed no clear difference in clinical improvement (low certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 0.65 [0.03, 14.52]
2 studies · 154 participants
Low