Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Guidewire‐assisted cannulation vs contrast‐assisted cannulation

Overall success of cannulation · Patients undergoing diagnostic or therapeutic ERCP

Guidewire‐assisted cannulation showed no clear difference in overall cannulation success compared with contrast‐assisted cannulation (moderate certainty).

1 finding from 1 review

Guidewire‐assisted cannulation vs contrast‐assisted cannulation

Post‐sphincterotomy bleeding · Patients undergoing diagnostic or therapeutic ERCP

Guidewire‐assisted cannulation showed no clear difference in post‐sphincterotomy bleeding compared with contrast‐assisted cannulation (low certainty).

1 finding from 1 review

Guidewire‐assisted cannulation vs contrast‐assisted cannulation

Perforation · Patients undergoing diagnostic or therapeutic ERCP

It is very uncertain whether guidewire‐assisted cannulation changes perforation compared with contrast‐assisted cannulation (very low certainty).

1 finding from 1 review

Point‐of‐care biomarkers (procalcitonin) for infection vs usual care

Clinical recovery · people with acute respiratory infections

The review found no eligible studies for this question.

2 findings from 1 review

Point‐of‐care biomarkers (C‐reactive protein) for infection vs usual care

Clinical recovery · people with acute respiratory infections
2 findings from 1 review

Intentional endometrial injury vs no intervention or a sham procedure

Live birth · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)

Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).

1 finding from 1 review

Exercise vs control

Falls · people with Parkinson's disease

Summary of findings for exercise probably leads to lower rate of Falls (falls per person‐year) compared with control (moderate certainty).

1 finding from 1 review