Heparin vs normal saline solution locking
- Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults 2022 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 1788 participantsLow
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It is very uncertain whether heparin changes CVC‐related bloodstream infections (positive microbiological… compared with normal saline solution locking (very low certainty).
It is very uncertain whether heparin changes mortality compared with normal saline solution locking (very low certainty).
It is very uncertain whether heparin changes haemorrhage from any site compared with normal saline solution locking (very low certainty).
It is very uncertain whether heparin changes heparin‐induced thrombocytopaenia compared with normal saline solution locking (very low certainty).
Vitamin A supplementation leads to lower all‐cause mortality compared with placebo or usual care (high certainty).
Vitamin A supplementation probably leads to higher vomiting compared with placebo or usual care (moderate certainty).
Vitamin A supplementation probably leads to lower vitamin A deficiency compared with placebo or usual care (moderate certainty).
Vitamin A supplementation leads to lower mortality due to diarrhoea compared with placebo or usual care (high certainty).
Vitamin A supplementation showed no clear difference in mortality due to measles compared with placebo or usual care (low certainty).
Vitamin A supplementation showed no clear difference in mortality due to LRTI compared with placebo or usual care (low certainty).
Vitamin A supplementation may leads to lower diarrhoea incidence Mean episodes per child per year compared with placebo or usual care (low certainty).
Vitamin A supplementation probably leads to lower measles incidence Mean episodes of measles per child per year compared with placebo or usual care (moderate certainty).
Vitamin A supplementation showed no clear difference in LRTI incidence Mean episodes per child per year compared with placebo or usual care (low certainty).
Vitamin A supplementation probably leads to lower bitot's spots incidence compared with placebo or usual care (moderate certainty).
Vitamin A supplementation probably leads to lower night blindness incidence compared with placebo or usual care (moderate certainty).
Guidewire‐assisted cannulation probably leads to lower post‐ERCP pancreatitis (PEP) compared with contrast‐assisted cannulation (moderate certainty).
Guidewire‐assisted cannulation may leads to higher primary cannulation success compared with contrast‐assisted cannulation (low certainty).
Guidewire‐assisted cannulation showed no clear difference in overall cannulation success compared with contrast‐assisted cannulation (moderate certainty).
Guidewire‐assisted cannulation showed no clear difference in post‐sphincterotomy bleeding compared with contrast‐assisted cannulation (low certainty).