Heparin vs normal saline solution locking: Haemorrhage
It is very uncertain whether heparin changes haemorrhage from any site compared with normal saline solution locking (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Heparin vs normal saline solution locking Haemorrhage from any site · adults with CVCs It is very uncertain whether heparin changes haemorrhage from any site compared with normal saline solution locking (very low certainty). Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults (2022) · Cochrane Headline outcomes only | RR 1.54 | 3 studies · 1197 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.