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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mobile bearing vs fixed bearing prosthesis Health‐related quality of life ‐ measured as SF‐12 PCS SF‐12 PCS. Scale from 0 to 100 (higher scores indicate better health‐related quality of life) · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients… Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for… (2015) · Cochrane | no estimate extracted | 3 studies · 498 participants | Low |
Mobile bearing vs fixed bearing prosthesis Revision surgery · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients… Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for… (2015) · Cochrane | RR 0.8 | 17 studies · 2065 participants | Low |
Mobile bearing vs fixed bearing prosthesis Mortality · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients… Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for… (2015) · Cochrane | RR 0.69 | 4 studies · 188 participants | Low |
Mobile bearing vs fixed bearing prosthesis Reoperation rate · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients… Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for… (2015) · Cochrane | RR 1.01 | 17 studies · 2065 participants | Low |
Mobile bearing vs fixed bearing prosthesis Other serious adverse events · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients… Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for… (2015) · Cochrane | RR 1.16 | 17 studies · 1732 participants | Low |
Intervention NR Pain on walking (VAS) Scale from 0 to 10 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 115 participants | Low |
Valgus knee brace vs no brace Function HSS: scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 110 participants | Low |
Valgus knee brace vs no brace Health‐related quality of life EQ‐5S: scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 117 participants | Low |
Valgus knee brace vs no brace Treatment failure · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs no brace Serious adverse events · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs no brace Total number of adverse events (withdrawals due to lack of effect)d · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 117 participants | Low |
Lateral wedge insole vs neutral insole Pain NRS: scale from 0 to 10 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 2 studies · 224 participants | Moderate |
Lateral wedge insole vs neutral insole Stiffness WOMAC: scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 3 studies · 358 participants | Moderate |
Lateral wedge insole vs neutral insole Function WOMAC: scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 3 studies · 358 participants | Moderate |
Lateral wedge insole vs neutral insole Health‐related quality of life HRQoL: scale from 0 to 1.0 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 179 participants | Moderate |
Lateral wedge insole vs neutral insole Treatment failure · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Knee function (HSS) Scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 110 participants | Low |
Lateral wedge insole vs neutral insole Serious adverse events · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Lateral wedge insole vs neutral insole Total number of adverse events · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs lateral wedge insole Pain VAS: scale from 0 to 10 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 91 participants | Low |
Valgus knee brace vs lateral wedge insole Stiffness · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs lateral wedge insole Function WOMAC: scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 91 participants | Low |
Valgus knee brace vs lateral wedge insole Health‐related quality of life · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs lateral wedge insole Treatment failure · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs lateral wedge insole Serious adverse events · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Valgus knee brace vs lateral wedge insole Total number of adverse events · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life (EQ‐5D) Scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 117 participants | Low |
Intervention NR Total number of adverse events (withdrawals due to lack of effect)c · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | RR 1.63 [0.94, 2.82] | 1 study · 117 participants | Low |
Intervention NR Pain on walking (NRS) Scale from 0 to 10 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 2 studies · 224 participants | Moderate |
Intervention NR Physical function (WOMAC) ‐ 12 months Scale from 0 to 100 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 3 studies · 358 participants | Moderate |
Intervention NR Health‐related quality of life (HRQoL) Scale from 0 to 1.0 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 179 participants | Moderate |
Valgus knee brace vs no brace Pain VAS: scale from 0 to 10 · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 1 study · 115 participants | Low |
Valgus knee brace vs no brace Stiffness · patients with varus medial osteoarthritis of the knee Braces and orthoses for treating osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain Self‐report questionnaires. Scale from 0‐100 (0 represents no pain) · patients with knee OA Exercise for osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 44 studies · 3537 participants | High |
Intervention NR Physical function Self‐report questionnaire. Scale from 0‐100 (0 represents no physical disability) · patients with knee OA Exercise for osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 44 studies · 3913 participants | Moderate |
Intervention NR Quality of life Self‐report questionnaire. Scale from 0‐100 (100 is maximum quality of life) · patients with knee OA Exercise for osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 13 studies · 1073 participants | High |
Intervention NR Study withdrawals or dropouts · patients with knee OA Exercise for osteoarthritis of the knee (2015) · Cochrane | no estimate extracted | 44 studies · 4607 participants | High |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T) Pain 100mm VAS . Scale from: 0 to 100. · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | 3 studies · 162 participants | Low |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR) Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR) Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR) Adverse events Complications reported · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | RR 1.41 [0.27, 7.28] | 1 study · 31 participants | Low |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR) Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and ligament reconstruction (T and LR) Trapeziometacarpal joint imaging Scapho‐metacarpal distance · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | 1 study · 20 participants | Low |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Pain ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Physical function ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Quality of life ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Global assessment ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Adverse events complications reported · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | RR 1.36 [0.48, 3.88] | 1 study · 100 participants | Moderate |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy (T) Physical function DASH Score. Scale from: 0 to 100. · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | 3 studies · 211 participants | Low |
Trapeziectomy with ligament reconstruction and tendon interposition (T and LRTI) vs trapeziectomy and interpositional arthroplasty (T and IA) Treatment failure ‐ not measured · Patients with thumb (trapeziometacarpal joint) osteoarthritis Surgery for thumb (trapeziometacarpal joint) osteoarthritis (2015) · Cochrane | no estimate extracted | NR | No studies |