Findings

What do systematic reviews say?

973 questions · 1,024 findings · 106 reviews

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No studies found 235 · 22.9%GRADE not reported 59 · 5.8%Very low 207 · 20.2%Low 271 · 26.5%Moderate 177 · 17.3%High 75 · 7.3%

Vitamin D vs placebo or no treatment

Graft loss · preventing bone disease in kidney transplant recipients

It is very uncertain whether vitamin D changes graft loss compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for preventing bone disease in kidney transplant recipients 2019 · Cochrane Headline outcomes only
RR 0.11 [0.01, 2.01]
3 studies · 220 participants
Very low

Vitamin D vs placebo or no treatment

Fracture · preventing bone disease in kidney transplant recipients

It is very uncertain whether vitamin D changes fracture compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for preventing bone disease in kidney transplant recipients 2019 · Cochrane Headline outcomes only
RR 0.96 [0.1, 8.94]
5 studies · 299 participants
Very low

Vitamin D vs placebo or no treatment

Acute rejection · preventing bone disease in kidney transplant recipients

It is very uncertain whether vitamin D changes acute graft rejection compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for preventing bone disease in kidney transplant recipients 2019 · Cochrane Headline outcomes only
RR 0.98 [0.52, 1.86]
5 studies · 385 participants
Very low

Vitamin D vs placebo

All‐cause mortality · adults with HIV infection

It is very uncertain whether vitamin D changes mortality compared with placebo (very low certainty).

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
RR 1.15 [0.65, 2.02]
1 study · 131 participants
Very low

Vitamin D vs placebo

Morbidity · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vitamin D vs placebo

CD4 cell count · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 288 participants
Low

Vitamin D vs placebo

Viral load · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Vitamin A vs placebo

All‐cause mortality · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vitamin A vs placebo

Morbidity · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vitamin A vs placebo

CD4 cell count · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 464 participants
Low

Vitamin A vs placebo

Viral load · adults with HIV infection

1 finding from 1 review

Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 495 participants
Low

SoF vitamin E vs placebo

Hot flush frequency (number/day) · patients with hot flushes in women with a history of breast cancer

1 finding from 1 review

Non‐hormonal interventions for hot flushes in women with a history of breast cancer 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 104 participants
High

SoF vitamin E vs placebo

Hot flushes score Number of HF x severity (from 1 to 4) ( · patients with hot flushes in women with a history of breast cancer

1 finding from 1 review

Non‐hormonal interventions for hot flushes in women with a history of breast cancer 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 104 participants
High

Vitamin E vs Placebo (not a true placebo)

Mucositis eradicated · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Vitamin E showed no clear difference in mucositis eradicated compared with placebo (not a true placebo); GRADE not reported.

1 finding from 1 review

Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
RR 6.00 [0.89, 40.31]
1 study · 18 participants
GRADE not reported

Vitamin A plus iron plus folate vs iron plus folate

Any adverse effects · pregnant women

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin supplementation for preventing miscarriage 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any intermittent iron regimen (with or without other vitamins and minerals) vs daily regimen (with same vitamins and minerals)‐maternal outcomes

Low birthweight · Women receiving supplements in pregnancy

Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in low birthweight (less than 2500 g) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).

1 finding from 1 review

Intermittent oral iron supplementation during pregnancy 2015 · Cochrane Headline outcomes only
RR 0.82 [0.55, 1.22]
8 studies · 1898 participants
Low

Any intermittent iron regimen (with or without other vitamins and minerals) vs daily regimen (with same vitamins and minerals)‐maternal outcomes

Participants with at least some Side Effects · Women receiving supplements in pregnancy

It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes side effects (any reported throughout intervention period) compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).

1 finding from 1 review

Intermittent oral iron supplementation during pregnancy 2015 · Cochrane Headline outcomes only
RR 0.56 [0.37, 0.84]
11 studies · 1777 participants
Very low

Any intermittent iron regimen (with or without other vitamins and minerals) vs daily regimen (with same vitamins and minerals)‐maternal outcomes

Severe anaemia at any time during second and third trimester (Hb less than 70 g/L) · Women receiving supplements in pregnancy

1 finding from 1 review

Intermittent oral iron supplementation during pregnancy 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1240 participants
Very low

Any intermittent iron regimen (with or without other vitamins and minerals) vs daily regimen (with same vitamins and minerals)‐maternal outcomes

Maternal clinical malaria or other infection in pregnancy · Women receiving supplements in pregnancy

Any intermittent iron regimen (with or without other vitamins and… led to lower maternal clinical malaria or other infection in pregnancy compared with daily regimen (with same vitamins and minerals)‐maternal outcomes; GRADE not reported.

1 finding from 1 review

Intermittent oral iron supplementation during pregnancy 2015 · Cochrane Headline outcomes only
RR 0 [0, 0]
0 studies · 0 participants
GRADE not reported

Any intermittent iron regimen (with or without other vitamins and minerals) vs daily regimen (with same vitamins and minerals)‐maternal outcomes

Birthweight (g) · Women receiving supplements in pregnancy

Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in birthweight (g) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).

1 finding from 1 review

Intermittent oral iron supplementation during pregnancy 2015 · Cochrane Headline outcomes only
MD 5.13
9 studies · 1939 participants
Low