Stroke · middle‐aged US male physicians
Vitamin C supplementation showed no clear difference in total stroke (fatal and non‐fatal) Physicians compared with placebo (low certainty).
1 finding from 1 review
Self‐reported CABG/PTCA Participant self‐reports · middle‐aged US male physicians
Vitamin C supplementation showed no clear difference in self‐reported CABG/PTCA Participant self‐reports compared with placebo (low certainty).
1 finding from 1 review
Self‐reported angina Participant self‐reports · middle‐aged US male physicians
Vitamin C supplementation showed no clear difference in self‐reported angina Participant self‐reports compared with placebo (low certainty).
1 finding from 1 review
Adverse events · people with sickle cell disease
1 finding from 1 review
Pain: presence of pain (slight or moderate) at 1 year · people with sickle cell disease
Vitamin D 100,000 IU/month showed no clear difference in presence of pain compared with 12,000 IU/month (moderate certainty).
1 finding from 1 review
Acute chest syndrome ( · people with sickle cell disease
1 finding from 1 review
Respiratory infections · people with sickle cell disease
1 finding from 1 review
HRQoL (using a validated scale) · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total body BMD measured by DEXA (% change from baseline) · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall improvement in CTS: SSS: short term (< 3 months) Scale from: 1 to 5 · carpal tunnel syndrome
1 finding from 1 review
Overall improvement in CTS: SSS: long term ‐ not measured · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall improvement in CTS: FSS: short term (< 3 months) Scale from: 1 to 5 · carpal tunnel syndrome
1 finding from 1 review
Overall improvement in CTS: FSS: long term ‐ not reported · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · carpal tunnel syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Frequency of leg cramps after treatment: never · treating leg cramps in pregnancy
1 finding from 1 review
Any adverse effects · pregnant women
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Low birthweight · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in low birthweight (less than 2500 g) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).
1 finding from 1 review
Participants with at least some Side Effects · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes side effects (any reported throughout intervention period) compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Severe anaemia at any time during second and third trimester (Hb less than 70 g/L) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal clinical malaria or other infection in pregnancy · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… led to lower maternal clinical malaria or other infection in pregnancy compared with daily regimen (with same vitamins and minerals)‐maternal outcomes; GRADE not reported.
1 finding from 1 review