Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

973 questions · 1,024 findings · 106 reviews

No studies found 235 · 22.9%GRADE not reported 59 · 5.8%Very low 207 · 20.2%Low 271 · 26.5%Moderate 177 · 17.3%High 75 · 7.3%

Vitamin D plus calcium vs calcium

Healing of rickets (number) Definition: normal alkaline phosphatase and bone radiograph

It is very uncertain whether vitamin D plus calcium changes healing of rickets (number) Definition: normal alkaline phosphatase… compared with calcium (very low certainty).

1 finding from 1 review

Vitamin D plus calcium vs calcium

Adverse events (number) Asymptomatic hypercalcaemia and hypercalciuria

It is very uncertain whether vitamin D plus calcium changes adverse events (number) Asymptomatic hypercalcaemia and hypercalciuria compared with calcium (very low certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A vs no supplementation

Death or chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A probably leads to lower death or chronic lung disease (oxygen use at 28 days) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A vs no supplementation

Death before 36 weeks' postmenstrual age · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in death before 36 weeks' postmenstrual age compared with no supplementation (moderate certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Neurodevelopmental impairment at 18 to 22 months · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in neurodevelopmental impairment at 18 to 22 months compared with no supplementation (low certainty).

1 finding from 1 review