Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

NSAIDS plus steroids vs steroids

Poor vision due to MO at 12 months after surgery · patients undergoing cataract surgery

It is very uncertain whether NSAIDS plus steroids changes poor vision due to MO at 12 months after surgery compared with steroids (very low certainty).

1 finding from 1 review

Intervention not reported

Postoperative sedation 12 hours after surgery (units of RSS, Ramsay Sedation Scale from 1 = Anxious or agitated or restless to 6 = Unresponsive) (MD, 95% CI) · adults having abdominal surgery
1 finding from 1 review

Regular‐dose postoperative 5‐Fluorouracil vs control

Intraocular pressure ( · participants with glaucoma surgery
3 findings from 1 review

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ epithelial toxicity ‐ combined surgery · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil may leads to higher complications ‐ epithelial toxicity ‐ combined surgery compared with control (low certainty).

1 finding from 1 review

Intraoperative 5‐Fluorouracil vs placebo or control

Failure at 12 months Need for repeat surgery or uncontrolled IOP (usually more than 22 mm Hg) despite additional topical or systemic medications · participants with glaucoma surgery

Intraoperative 5‐Fluorouracil leads to lower failure at 12 months Need for repeat surgery or uncontrolled IOP… compared with placebo or control (high certainty).

1 finding from 1 review