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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Functional impairment · women with perinatal depression

Lay health worker‐led psychosocial interventions showed no clear difference in functional impairment ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Service utilisation ‐ maternal or child hospitalisations ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to higher recovery from CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Prevalence of CMDs ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by SRQ‐20 > 7b; PHQ‐9 ≥ 11d (RR < 1 denotes lower prevalence compared to control) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower prevalence of CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review