Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,231 questions · 3,354 findings · 394 reviews

No studies found 803 · 23.9%GRADE not reported 267 · 8%Very low 757 · 22.6%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Retinoic acid post‐consolidation therapy vs no further treatment

Overall survival (reported as mortality) · high‐risk neuroblastoma patients treated with autologous HSCT

Retinoic acid postconsolidation therapy showed no clear difference in overall survival (reported as mortality) compared with no further treatment (low certainty).

1 finding from 1 review

Retinoic acid post‐consolidation therapy vs no further treatment

Event‐free survival · high‐risk neuroblastoma patients treated with autologous HSCT

Retinoic acid postconsolidation therapy showed no clear difference in event‐free survival (reported as relapse, disease progression, death… compared with no further treatment (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Absence of nausea ( · people with chemotherapy‐induced nausea and vomiting

It is very uncertain whether cannabinoid plus other anti‐emetic agent changes absence of nausea ( compared with other anti‐emetic monotherapy (very low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Absence of vomiting ( · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in absence of vomiting ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Absence of nausea and vomiting ( · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in absence of nausea and vomiting ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in withdrawal any reason ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Withdrawals due to adverse events · people with chemotherapy‐induced nausea and vomiting

It is very uncertain whether cannabinoid plus other anti‐emetic agent changes withdrawal due to adverse event ( compared with other anti‐emetic monotherapy (very low certainty).

1 finding from 1 review

Cannabinoid plus other anti‐emetic agent vs other anti‐emetic monotherapy

Lack of efficacy withdrawal · people with chemotherapy‐induced nausea and vomiting

Cannabinoid plus other anti‐emetic agent showed no clear difference in withdrawal due to lack of efficacy ( compared with other anti‐emetic monotherapy (low certainty).

1 finding from 1 review