Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

CBT vs WAIT LIST

Acceptability (number of participants lost to post‐treatment assessment) · children and adolescents with anxiety disorders

CBT showed no clear difference in acceptability (number of participants lost to post‐treatment… compared with waitlist (low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: disengagement from services(assessment varied) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams may leads to lower service use: disengagement from services(assessment varied) compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Resilience interventions vs controls

Resilience Measured by: investigators measured resilience using different instruments; higher scores mean higher resilience Timing of outcome assessment: post‐intervention · healthcare students, including students in training for health professions delivering direct medical care (e.g. medical students, nursing…
1 finding from 1 review

Resilience interventions vs controls

Mental health and well‐being: depressionMeasured by: investigators measured depression using different instruments; lower scores mean lower depression Timing of outcome assessment: post‐intervention · healthcare students, including students in training for health professions delivering direct medical care (e.g. medical students, nursing…
1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether video modelling acclimatisation changes self- or observational assessment of intraoperative… compared with acclimatisation in clinic (tell-show-do) (very low certainty).

1 finding from 1 review

Counter-stimulation or distraction vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether counter-stimulation or distraction changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs Sleeper One (electronic LA delivery system)

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour (any disruptive behaviour/sudden reaction/movement) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether the wand (computer-controlled LA delivery system) changes self- or observational assessment of intraoperative… compared with sleeper One (electronic LA delivery system) (very low certainty).

1 finding from 1 review

Sesame oil vs Chlorhexidine mouthwash

OLT score and patient self-assessment (BANA test) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Asokan 2011 (2-arm trial) compared sesame oil versus chlorhexidine 0.2% mouthwash (OLT and BANA test). We could not include the results in the meta-analysis because they did not report post-intervention OLT score and P…
    1 study
    GRADE not reported

Special manual toothbrush (self, carer or carer-assisted brushing) vs Manual toothbrush

Oral health assessment and oral bacteria levels (medium term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified
1 finding from 1 review
  • Oral hygiene interventions for people with intellectual disabilities 2019 · Cochrane All outcomes
    Medium term (6 weeks to 12 months)
    Comparison 1.5 (graded in the Effects of interventions text; not tabulated in the SoF). Single-use suction toothbrush vs standard manual toothbrush (both with a chemical agent), 90 days, Ferozali 2007: Total Oral…
    1 study · 22 participants
    Very low

Salvadora persica (miswak) mouthrinse vs Chlorhexidine mouthwash

Patient self-assessment VAS (scale 0 to 10) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether miswak (Salvadora persica) mouthwash changes patient self-assessment VAS (scale 0 to 10) compared with chlorhexidine mouthwash (very low certainty).

1 finding from 1 review

Antibiotics vs control

Active trachoma · people (any age) with active trachoma

Antibiotic may leads to lower active trachoma Clinical assessment: active trachoma defined as TF,… compared with control (low certainty).

1 finding from 1 review