Intervention not reported
- Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis 2015 · Cochrane Headline outcomes onlyno estimate extracted7 participantsVery low
Rifampicin plus pyrazinamide leads to higher treatment‐limiting adverse events compared with isoniazid (high certainty).
Rifapentine plus isoniazid weekly probably leads to higher treatment‐limiting adverse events compared with isoniazid daily (moderate certainty).
It is very uncertain whether rifampicin changes treatment‐limiting adverse events compared with isoniazid (very low certainty).
Rifampicin plus isoniazid showed no clear difference in treatment‐limiting adverse events compared with isoniazid (low certainty).
Anticholinergics showed no clear difference in mean change from baseline in condition‐specific quality of lifeScale… compared with placebo (low certainty).
Anticholinergics probably leads to higher patient perception of cure or improvement compared with placebo (moderate certainty).
Anticholinergics showed no clear difference in mean number of urgency episodes per 24 hours compared with placebo (moderate certainty).
Anticholinergics may leads to higher adverse events: dry mouth compared with placebo (low certainty).
Anticholinergics may leads to higher adverse events:urinary retention compared with placebo (low certainty).
Anticholinergics may leads to higher withdrawal due to adverse events compared with placebo (low certainty).
Anticholinergics showed no clear difference in mean number of micturitions per 24 hours compared with placebo (moderate certainty).
Macrolides showed no clear difference in clinical cure: syndromic approach compared with any other antibiotic (low certainty).
Macrolides showed no clear difference in clinical cure: aetiological approach compared with any other antibiotic (low certainty).
It is very uncertain whether macrolides changes clinical improvement: syndromic approach compared with any other antibiotic (very low certainty).
Macrolides showed no clear difference in clinical improvement: aetiological approach compared with any other antibiotic (low certainty).
Macrolides showed no clear difference in microbiological cure compared with any other antibiotic (low certainty).