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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,653 questions in 194 reviews · Gynaecology and Fertility

current versions
No studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: preterm delivery · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 8.02 [1.72, 37.33]1 study · 120 participantsLow
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Live birth (or ongoing pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.88 [0.43, 1.81]1 study · 132 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.94 [0.63, 5.96]1 study · 132 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.24 [0.66, 2.35]2 studies · 172 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Ongoing pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.09 [0.33, 3.63]1 study · 73 participantsVery low
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.9 [0.31, 2.6]1 study · 73 participantsVery low
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.96 [0.13, 7.09]1 study · 94 participantsVery low
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.55 [0.64, 3.76]1 study · 94 participantsVery low
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Adverse events: ectopic pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.94 [0.12, 73.95]1 study · 94 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Live birth (or ongoing pregnancy) · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.38 [1.16, 4.86]6 studies · 564 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.54 [0.59, 4.01]5 studies · 504 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.22 [1.5, 3.27]9 studies · 824 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: multiple pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.68 [0.81, 8.88]2 studies · 240 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: ectopic pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.94 [0.12, 73.95]1 study · 94 participantsVery low
Summary of findings table ‐ ICSI vs c‐IVF
Live Birth · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 1.11 [0.94, 1.3]2 studies · 1124 participantsLow
Summary of findings table ‐ ICSI vs c‐IVF
Multiple Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 0.89 [0.66, 1.2]2 studies · 1479 participantsModerate
Summary of findings table ‐ ICSI vs c‐IVF
Ectopic Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 1 [0.42, 2.38]1 study · 1064 participantsModerate
Summary of findings table ‐ ICSI vs c‐IVF
Pre‐Eclampsia · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 1 [0.06, 15.95]1 study · 1064 participantsModerate
Summary of findings table ‐ ICSI vs c‐IVF
Prematurity · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 0.75 [0.53, 1.06]1 study · 1064 participantsModerate
Summary of findings table ‐ ICSI vs c‐IVF
Clinical Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 1 [0.88, 1.13]3 studies · 1539 participantsLow
Summary of findings table ‐ ICSI vs c‐IVF
Viable intrauterine Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 1 [0.86, 1.16]2 studies · 1479 participantsModerate
Summary of findings table ‐ ICSI vs c‐IVF
Miscarriage · : Couples with males presenting normal total sperm count and motility were included in this review.
Intracytoplasmic sperm injection versus conventional in vitro fertilisation in couples with males presenting… (2023) · Cochrane
RR 0.96 [0.58, 1.61]1 study · 1064 participantsModerate
Combined OCP vs placebo or no treatment
Pain score ( · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extracted6 studies · 588 participantsHigh
Combined low‐dose OCP vs another combined low‐dose OCP
Absence from work or school · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 1.12 [0.64, 1.99]1 study · 445 participantsVery low
NSAID vs combined OCP
Pain score (measured on VAS; 0–100; lower score is better) · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extracted1 study · 91 participantsLow
NSAID vs combined OCP
Pain improvement · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Adverse events · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Requirement for additional medication · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
NSAID vs combined OCP
Absence from work or school · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
Combined OCP vs placebo or no treatment
Pain improvement (assessed as improvement from 1 major category to next) · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 1.65 [1.29, 2.1]6 studies · 717 participantsLow
Combined OCP vs placebo or no treatment
Adverse events · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 1.31 [1.2, 1.43]7 studies · 1025 participantsModerate
Combined OCP vs placebo or no treatment
Requirement for additional medication · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 0.63 [0.4, 0.98]2 studies · 163 participantsLow
Combined OCP vs placebo or no treatment
Absence from work or school · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 0.63 [0.41, 0.97]2 studies · 148 participantsLow
Combined low‐dose OCP vs another combined low‐dose OCP
Pain score ( · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extracted2 studies · 106 participantsLow
Combined low‐dose OCP vs another combined low‐dose OCP
Pain improvement · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 1.06 [0.65, 1.74]1 study · 326 participantsModerate
Combined low‐dose OCP vs another combined low‐dose OCP
Adverse events for continuous vs standard regimen OCP · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
RR 1.11 [1.01, 1.22]3 studies · 602 participantsLow
Combined low‐dose OCP vs another combined low‐dose OCP
Requirement for additional medication · women with primary dysmenorrhoea
Combined oral contraceptive pill for primary dysmenorrhoea (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs expectant management
Live birth per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 22 [2.56, 189.37]1 study · 51 participantsVery low
IVF vs unstimulated IUI
Miscarriage rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 1.72 [0.14, 21.25]1 study · 43 participantsVery low
IVF vs IUI + ovarian stimulation with gonadotropins or CC
Live birth rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 1.19 [0.87, 1.61]3 studies · 731 participantsLow
IVF vs IUI + ovarian stimulation with gonadotropins or CC
Clinical pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 1.17 [0.85, 1.59]3 studies · 731 participantsLow
IVF vs IUI + ovarian stimulation with gonadotropins or CC
Multiple pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 0.82 [0.38, 1.77]3 studies · 731 participantsLow
IVF vs IUI + ovarian stimulation with gonadotropins or CC
OHSS rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 6.86 [0.35, 134.59]1 study · 207 participantsVery low
IVF vs IUI + ovarian stimulation with gonadotropins or CC
Miscarriage rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 0.31 [0.03, 3.04]1 study · 207 participantsVery low
IVF vs expectant management
Clinical pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
OR 3.24 [1.07, 9.8]2 studies · 86 participantsVery low
IVF vs expectant management
Multiple pregnancy rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies
IVF vs expectant management
OHSS rate per woman randomised · women with unexplained subfertility
In vitro fertilisation for unexplained subfertility (2023) · Cochrane
no estimate extractedNRNo studies