Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including smokers: OR 2.50 (1.74 to 3.59) for preterm birth, significant.
1 finding from 1 review
OR 2.50 [1.74, 3.59]
8 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies excluding participants with co-morbidities: OR 2.53 (1.45 to 4.42) for preterm birth, significant.
1 finding from 1 review
OR 2.53 [1.45, 4.42]
6 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Pregnant women with periodontitis probably have a small increased risk of preterm birth (moderate certainty).
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=2 affected teeth: OR 2.31 (1.60 to 3.34) for preterm birth, significant.
1 finding from 1 review
OR 2.31 [1.60, 3.34]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=4 teeth with PPD >=4 mm and CAL >=3 mm at the same site: OR 2.86 (1.79 to 4.56) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including participants with history of urinary tract infection: OR 2.38 (1.63 to 3.49) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Study design: cohort: OR 2.07 (1.48 to 2.89) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=1 affected tooth: OR 1.63 (1.16 to 2.31) for preterm birth, significant.
1 finding from 1 review
OR 1.63 [1.16, 2.31]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies excluding smokers: OR 1.71 (0.96 to 3.05) for preterm birth, not significant.
1 finding from 1 review
OR 1.71 [0.96, 3.05]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Continent: North America: OR 2.27 (1.82 to 2.84) for preterm birth, significant.
1 finding from 1 review
OR 2.27 [1.82, 2.84]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Risk of bias: low: OR 2.49 (1.82 to 3.42) for preterm birth, significant.
1 finding from 1 review
OR 2.49 [1.82, 3.42]
9 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Continent: Europe: OR 1.77 (1.28 to 2.44) for preterm birth, significant.
1 finding from 1 review
OR 1.77 [1.28, 2.44]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=3 mm CAL: OR 2.50 (1.60 to 3.90) for preterm birth, significant.
1 finding from 1 review
OR 2.50 [1.60, 3.90]
6 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=1 mm CAL: OR 2.87 (1.65 to 4.99) for preterm birth, significant.
1 finding from 1 review
OR 2.87 [1.65, 4.99]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including participants with co-morbidities: OR 2.16 (1.54 to 3.03) for preterm birth, significant.
1 finding from 1 review
OR 2.16 [1.54, 3.03]
4 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Examined teeth: full mouth without specification on third molars: OR 2.77 (1.72 to 4.44) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Risk of bias: high: OR 1.60 (0.75 to 3.44) for preterm birth, not significant.
1 finding from 1 review
OR 1.60 [0.75, 3.44]
2 studies
GRADE not reported
Preterm birth stratified by clinical type (spontaneous vs iatrogenic vs term) · pregnant women
The planned subanalysis by type of preterm birth (spontaneous vs iatrogenic vs term) could not be performed because of the small number of cases and lack of information in the original studies.
1 finding from 1 review
Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomesPregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs · By type of PTB (spontaneous vs iatrogenic)
no estimate extracted
0 studies
GRADE not reported
Preterm birth stratified by gestational age at birth (moderate-to-late 32 to <37, very 28 to <32, extremely <28 weeks) · pregnant women
The planned subanalysis of preterm birth by gestational age at birth (moderate-to-late, very, extremely preterm) could not be performed because of the small number of cases and lack of stratified data in the original studies.
1 finding from 1 review
Dental caries and preterm birth: a systematic review and meta-analysis. 2018 All outcomesPregnant women assessed around delivery in observational studies across multiple countries (Mexico, Malawi, India, France, Jordan, Finland, Tanzania); mostly retrospective cohort and case-control designs · By gestational age at birth
no estimate extracted
0 studies
GRADE not reported
Gestational age (preterm birth < 37 weeks) · pregnant women
Pregnant women with dental caries did not have a significantly increased risk of preterm birth (pooled OR 1.16, 95% CI 0.90 to 1.49; 5 studies; I2=35%); certainty of evidence not graded.
1 finding from 1 review