Duration of mechanical ventilation · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
It is very uncertain whether chlorhexidine (mouthrinse or gel), as part of oral hygiene care changes duration of mechanical ventilation compared with placebo or usual care (very low certainty).
1 finding from 1 review
Duration of ICU stay · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of ICU stay compared with placebo or usual care (low certainty).
1 finding from 1 review
Cost / economic data · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
The review found no eligible studies for this question.
1 finding from 1 review
Duration of systemic antibiotic use · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of systemic antibiotic use compared with placebo or usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol showed no clear difference in oral mucositis (moderate to severe) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol showed no clear difference in oral mucositis (severe) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Oral care protocol led to lower oral mucositis (any severity) compared with no treatment/usual care; GRADE not reported.
1 finding from 1 review
Quality of life (xerostomia-related) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Unstimulated whole saliva (UWS) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Commercial mouthcare system (Biotene Oral Balance / Xerostom) showed no clear difference in salivary flow (unstimulated whole saliva) compared with usual care or CMC-based control; GRADE not reported.
1 finding from 1 review
MD 0.02 [-0.02, 0.06]
2 studies
GRADE not reported
Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Commercial mouthcare system (Biotene Oral Balance / Xerostom) led to higher xerostomia (VAS mouth dryness) compared with usual care or CMC-based control; GRADE not reported.
1 finding from 1 review
SMD 1.11 [0.33, 1.89]
1 study
GRADE not reported
Plaque · Adults aged 22 to 57 years with mixed levels of ID; setting residential
1 finding from 1 review
Individualised oral care plan vs usual care. Subjective Oral Hygiene Rating scale 1-5 and Improvement Differential, mean 12 months; SOHR 2.97 (intervention) vs 3.10 (control); improvement differential 38% vs 5%; 79…
1 study · 79 participants
Very low
Calculus · Adults (mean age 30.9 years), level of ID unclear; setting day centre
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene… may leads to lower calculus (long term) compared with usual care (no specific treatment) (low certainty).
1 finding from 1 review
Gingival pocketing (long term) · Adults (mean age 30.9 years), level of ID unclear; setting day centre
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene… may leads to lower gingival pocketing (long term) compared with usual care (no specific treatment) (low certainty).
1 finding from 1 review
Plaque · Adults (mean age 30.9 years), level of ID unclear; setting day centre
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene… may leads to lower plaque (long term) compared with usual care (no specific treatment) (low certainty).
1 finding from 1 review
Gingival bleeding (various bleeding indices) · Adults (mean age 30.9 years), level of ID unclear; setting day centre
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene… showed no clear difference in gingival bleeding (long term) compared with usual care (no specific treatment) (low certainty).
1 finding from 1 review
Use of healthcare resources (cost effectiveness, time taken to fit, number of dental visits) · Children with high risk of dental decay
The review found no eligible studies for this question.
1 finding from 1 review
Economic: Increased costs of health care · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Caries experience · Children (mean age newborn to ~5.2 years) and their parents/carers
Oral-health-education-only interventions showed at most a marginal effect on tooth-level caries (dmft SMD -0.11, 95% CI -0.21 to -0.00; 2 studies; not GRADE-rated).
1 finding from 1 review
Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers
Oral-health-education-only interventions did not show a statistically significant effect on surface-level caries (dmfs SMD -0.20, 95% CI -0.43 to 0.03; 2 studies; not GRADE-rated).
1 finding from 1 review
Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers
Comprehensive interventions produced a small, statistically significant reduction in surface-level caries (dmfs SMD -0.14, 95% CI -0.26 to -0.02; 10 studies; not GRADE-rated).
1 finding from 1 review