Tramadol vs other opioids
It is very uncertain whether tramadol alone changes number of participants experiencing any serious adverse events compared with other opioids (very low certainty).
- RR 7.42 [0.39, 141]4 studies · 495 participantsVery low
It is very uncertain whether tramadol alone changes number of participants experiencing any serious adverse events compared with other opioids (very low certainty).
Tramadol alone probably leads to higher number of participants experiencing any adverse events compared with placebo (moderate certainty).
Tramadol alone probably leads to higher number of participants who withdrew due to adverse events compared with placebo (moderate certainty).
Tramadol alone may leads to higher number of participants experiencing any serious adverse events compared with placebo (low certainty).
Tramadol in combination with acetaminophen probably leads to higher number of participants experiencing any adverse event compared with placebo (moderate certainty).
Tramadol in combination with acetaminophen may leads to higher number of participants who withdrew due to adverse events compared with placebo (low certainty).
The review found no eligible studies for this question.
Tramadol in combination with acetaminophen showed no clear difference in number of participants experiencing any adverse event compared with NSAIDs (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.