Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

58 questions · 59 findings · 3 reviews

No studies found 2 · 3.4%GRADE not reported 11 · 18.6%Very low 19 · 32.2%Low 24 · 40.7%Moderate 3 · 5.1%High 0 · 0%

Ketoconazole vs ciclopirox

Side effects ‐ Scalp only Self reported · patients with seborrhoeic dermatitis

It is very uncertain whether ketoconazole changes side effects ‐ Scalp only Self reported compared with ciclopirox (very low certainty).

1 finding from 1 review

Ciclopirox vs placebo

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ciclopirox probably leads to lower failure to achieve complete resolution (combined for face and scalp)… compared with placebo (moderate certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Recurrence · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily showed no clear difference in relapse or recurrence Evidence of clinical or mycological infection… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Azoles vs allylamines

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes adverse effects Reported by investigators 'and' or 'or' participants compared with allylamines (very low certainty).

1 finding from 1 review

Azoles vs allylamines

Relapse or recurrence Evidence of clinical and mycological relapse after the end of treatment. Assessed in 3 studies · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes relapse or recurrence Evidence of clinical and mycological relapse… compared with allylamines (very low certainty).

1 finding from 1 review

Azoles vs moderate‐potent corticosteroid/azole combinations

Clinical cure · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes clinical cure (immediately at end of treatment) Resolution of… compared with moderate‐potent corticosteroid/azole combinations (very low certainty).

1 finding from 1 review

Azoles vs moderate‐potent corticosteroid/azole combinations

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes adverse effects Reported by investigators 'and' or 'or' participants compared with moderate‐potent corticosteroid/azole combinations (very low certainty).

1 finding from 1 review