Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

33 questions · 35 findings · 7 reviews · Airways

No studies found 3 · 8.6%GRADE not reported 3 · 8.6%Very low 6 · 17.1%Low 12 · 34.3%Moderate 11 · 31.4%High 0 · 0%

Intervention not reported

Number of subjects who had one or more exacerbations over the study period in children and adolescents ( · Adults and children with asthma

The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).

1 finding from 1 review

Tailoring asthma treatment using FeNO vs clinical symptoms

Asthma exacerbations · children with asthma

It is very uncertain whether tailoring asthma treatment using fractional exhaled nitric oxide changes number of asthma exacerbations per 52 weeks (exacerbation rate) compared with clinical symptoms (very low certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis
1 finding from 1 review

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Intervention not reported

Number of subjects who had one or more exacerbations over the study period in adults ( · Adults and children with asthma

The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).

1 finding from 1 review