Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Maternal · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Changed/stopped drugs due to maternal side‐effects · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in changed/stopped drugs due to maternal side‐effects compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Elective delivery (induction of labour + elective caesarean section) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in elective delivery (induction of labour + elective caesarean section) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Fetal/neonatal/infant · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Total reported fetal or neonatal deaths (including miscarriage) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Small‐for‐gestational age · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in small‐for‐gestational age compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review