Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

108 questions · 108 findings · 7 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 42 · 38.9%GRADE not reported 1 · 0.9%Very low 41 · 38%Low 20 · 18.5%Moderate 4 · 3.7%High 0 · 0%

Pregabalin vs placebo

Treatment‐related adverse effects · adults and children with sickle cell disease experiencing neuropathic pain

It is very uncertain whether summary of findings ‐ Pharmacological intervention (pregabalin) changes treatment‐related adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Compliance or adherence to the trial intervention (including satisfaction): use of intervention at least once · adults and children with hemophilia

Summary of findings ‐ DVD plus information booklet showed no clear difference in compliance or adherence to the trial intervention (including… compared with information booklet alone (low certainty).

1 finding from 1 review

Exercise vs no intervention

Adverse events · participants with haemophilia

The review found no eligible studies for this question.

1 finding from 1 review
  • Exercise for haemophilia 2016 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Exercise vs no intervention

Quality of life · participants with haemophilia

The review found no eligible studies for this question.

1 finding from 1 review
  • Exercise for haemophilia 2016 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Exercise vs no intervention

Functional ability · participants with haemophilia

The review found no eligible studies for this question.

1 finding from 1 review
  • Exercise for haemophilia 2016 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found