Findings

What do systematic reviews say?

33 questions · 33 findings · 4 reviews · Breast Cancer

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 5 · 15.2%Very low 8 · 24.2%Low 7 · 21.2%Moderate 8 · 24.2%High 5 · 15.2%

Summary of findings table ‐ Systemic therapy vs control

Effect on discontinuation of aromatase inhibitors (AI) · women with early breast cancer

Summary of findings table ‐ Systemic therapy showed no clear difference in effect on discontinuation of aromatase inhibitors (AI) compared with control (low certainty).

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
RR 0.16 [0.01, 2.99]
1 study · 147 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Effect on breast cancer‐specific quality of life (BCS‐QoL) · women with early breast cancer

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Health‐related quality of life (HRQoL) · women with early breast cancer

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Incidence of AIMSS · women with early breast cancer

It is very uncertain whether summary of findings table ‐ Systemic therapy changes incidence of AIMSS compared with control (very low certainty).

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
RR 0.82 [0.63, 1.06]
2 studies · 240 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in pain from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1099 participants
Very low

Summary of findings table ‐ Systemic therapy vs control

Change in stiffness from baseline to end of intervention · health problem or population

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 295 participants
Very low

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Locoregional recurrence · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) may leads to lower local and regional recurrence (LRR) compared with no PMRT (low certainty).

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
HR 0.2 [0.13, 0.33]
1 study · 552 participants
Low

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Overall survival (OS) · women with breast cancer and one to three positive lymph nodes

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) probably leads to lower overall survival (OS) compared with no PMRT (moderate certainty).

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
HR 0.76 [0.6, 0.97]
1 study · 552 participants
Moderate

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Disease-free survival · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Time to progression · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Short‐term adverse events · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

Long‐term adverse events · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Postmastectomy radiotherapy (PMRT) vs no PMRT

QoL · women with breast cancer and one to three positive lymph nodes

1 finding from 1 review

Post‐mastectomy radiotherapy for women with early breast cancer and one to three positive lymph nodes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported