Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

138 questions · 142 findings · 24 reviews

No studies found 28 · 19.7%GRADE not reported 7 · 4.9%Very low 31 · 21.8%Low 44 · 31%Moderate 30 · 21.1%High 2 · 1.4%

Slow passive expiration vs control

Change in the severity status of bronchiolitis Assessed using a variety of scales · infants up to 24 months of age with acute bronchiolitis

Slow passive expiration showed no clear difference in change in the severity status of bronchiolitis Assessed using a… compared with control (low certainty).

1 finding from 1 review

Two-band palatal expander with slow expansion vs Two-band palatal expander with rapid expansion

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
  • Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
    7 months after start of treatment
    Martina 2012: slow 6.3 mm (SD 2.1) vs rapid 5.7 mm (SD 1.6); reported as no statistically significant difference in text (PUB2 MD 0.60, 95% CI -0.85 to 2.05); Table 1 lists P<0.001 (discrepant)
    1 study · 26 participants
    GRADE not reported

Xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy vs Control (sorbitol) tablets

Number of infants with a caries increment (dmfs) · Infants (primary teeth)

It is very uncertain whether xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy changes number of infants with a caries increment (dmfs) compared with control (sorbitol) tablets (very low certainty).

1 finding from 1 review

Rapid vs slow withdrawal of antiepileptic drugs

Seizure freedom · people with epilepsy

It is very uncertain whether rapid changes seizure freedom after 1 year of AED withdrawal compared with slow withdrawal of antiepileptic drugs (very low certainty).

3 findings from 1 review