Cochrane · systematic review · CD005003
Rapid versus slow withdrawal of antiepileptic drugs
Ayuga Loro, F, Gisbert Tijeras, E, Brigo, F · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsRapid versus slow withdrawal of antiepileptic drugs
Population: people with epilepsy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Seizure freedom after 1 year of AED withdrawal Rapid vs slow withdrawal of antiepileptic drugs | RR 0.76 [0.58, 1.01] | 1 study · 149 participants | Very low Downgraded: risk of bias, imprecision |
Seizure freedom after 2 years of AED withdrawal Rapid vs slow withdrawal of antiepileptic drugs | RR 0.87 [0.58, 1.29] | 1 study · 149 participants | Very low Downgraded: risk of bias, imprecision |
Seizure freedom after 5 years of AED withdrawal Rapid vs slow withdrawal of antiepileptic drugs | RR 1.4 [0.54, 3.65] | 1 study · 149 participants | Very low Downgraded: risk of bias, imprecision |