Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

52 questions · 56 findings · 7 reviews

No studies found 30 · 53.6%GRADE not reported 0 · 0%Very low 9 · 16.1%Low 11 · 19.6%Moderate 6 · 10.7%High 0 · 0%

Any skin care procedure (method or frequency of application) vs any unstructured skin care procedure

Number of participants with IAD (residual, i.e. not healed) · adults with urinary incontinence

Any skin care procedure (method or frequency of application) probably leads to lower number of participants with IAD (residual, i.e. not healed) (1)… compared with any unstructured skin care procedure (moderate certainty).

1 finding from 1 review

Arginine butyrate plus standard care alone vs usual care

Ulcer healing · individuals with sickle cell disease and a leg ulcer

It is very uncertain whether arginine butyrate plus standard care alone changes complete leg ulcer closure (defined as 100% epithelization or skin… compared with standard care alone (very low certainty).

1 finding from 1 review