Findings

What do systematic reviews say?

22 questions · 22 findings · 1 reviews

No studies found 8 · 36.4%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 13.6%Moderate 6 · 27.3%High 5 · 22.7%

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Early leads to higher all known pregnancy loss (including termination of pregnancy) compared with second trimester amniocentesis (high certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.29 [1.03, 1.61]
1 study · 4334 participants
High

Miscarriage · prenatal diagnosis

Early showed no clear difference in spontaneous miscarriage compared with second trimester amniocentesis (moderate certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.41 [1, 1.98]
1 study · 4334 participants
Moderate