Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

40 questions · 41 findings · 6 reviews

No studies found 10 · 24.4%GRADE not reported 0 · 0%Very low 19 · 46.3%Low 11 · 26.8%Moderate 1 · 2.4%High 0 · 0%

Intervention vs no intervention or control intervention (control)

Serious adverse events (number) ‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes serious adverse events (proportion) ‐ pegylated interferon‐alpha… compared with no intervention or control intervention (control) (very low certainty).

2 findings from 1 review

Intervention vs no intervention or control intervention (control)

Chronic HCV infection†‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes chronic HCV infection†‐ pegylated interferon‐alpha plus ribavirin… compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review